Hepatitis E Virus RNA Screening

Date of reception of the dossier

22.09.2021

Notified Body number

2797

Internal PECP dossier #

In vitro diagnostic medical device

This test is intended to screen donor samples for HEV RNA in plasma samples from individual human donors, including
donors of whole blood, blood components (red cells,
platelets, and plasma), and other living donors.

Intended purpose

P1

what is detected and/or measured
please specify the analyte(s) or marker(s), e.g. SARS-CoV-2 spike protein, Kel1 (K)

P2

function of the device
e.g. diagnosis, aid to diagnosis, monitoring, determining the infectious load, tissue typing etc

This test is intended for use to screen
donor samples for HEV RNA in plasma
samples from individual human donors,
including donors of whole blood, blood
components (red cells, platelets, and
plasma), and other living donors.

P3

the specific disorder, condition or risk factor of
interest that it is intended to detect, define or
differentiate e.g. hepatitis C infection, exposure to SARS-CoV-2, risk of HIV transmission in blood transfusion etc.

Hepatitis E virus (HEV) transmission in
blood transfusion

P4

whether it is automated or not

Automated

P5

whether it is qualitative, semi-quantitative or
quantitative

Qualitative

P6

type of specimen(s)
e.g. whole blood, serum, saliva etc

Plasma

P7

where applicable, the testing population
e.g. persons with specific health conditions,
persons with specific symptoms, children in a
certain age range

Living donors of whole blood and blood
components.

P8

intended user

Trained laboratory professionals
proficient in using automated platform

Technology

T1

principle of the assay method or principles of operation of the instrument e.g. real-time PCR, qualitative PCR, digital PCR, sandwich immunoassay, competitive immunoassay, immunoturbidimetric assay etc.

Real-time PCR

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